INTEGRATIVE ANALYSIS OF BULK AND SINGLE-CELL RNA-SEQ REVEALS THE MOLECULAR CHARACTERIZATION OF THE IMMUNE MICROENVIRONMENT AND OXIDATIVE STRESS SIGNATURE IN MELANOMA

Integrative analysis of bulk and single-cell RNA-seq reveals the molecular characterization of the immune microenvironment and oxidative stress signature in melanoma

Background: The immune microenvironment and oxidative stress of melanoma show significant heterogeneity, which affects tumor growth, invasion and treatment response.Single-cell and bulk RNA-seq data were used to explore the heterogeneity of the immune microenvironment and oxidative stress of melanoma.Methods: The R package Seurat facilitated the an

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Node Localization Method in Wireless Sensor Networks Using Combined Crow Search and the Weighted Centroid Method

Node localization is critical for accessing diverse nodes that provide services in remote places.Single-anchor localization techniques suffer co-linearity, performing poorly.The reliable multiple anchor node selection method is computationally intensive and requires a lot of processing power and #5 KALI MUR 6X time to identify suitable anchor nodes

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Carbon information disclosure mechanism considering extended producer responsibility and low carbon preference under outsourcing remanufacturing

The implementation of EPR information disclosure responsibility is one of the four key tasks in the implementation of EPR.In order to explore the impact mechanism of carbon information disclosure behavior of manufacturers and remanufacturers considering extended producer responsibility (EPR) and low-carbon Emergency Lighting Batteries preference on

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Sporades jaechi sp. nov. with comments on classification of the New Caledonian genus Sporades Fauvel (Coleoptera, Carabidae, Trechini, Trechodina)

Sporades jaechi sp.nov.from Decor Poum, New Caledonia is newly described and shown to be a member of the monophyletic Sporades subgenus Perileptosporades Deuve, 2010.Sporades millei Giachino and S.schuhi Donabauer are newly recognized as members of the subgenus Perileptosporades, and a key to its species is provided.Although Perileptosporades can b

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